Dipeptidase deficiency and malabsorption of glycylglycine in disease states

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Dipeptidase deficiency and malabsorption of glycylglycine in disease states.

The activities of jejunal mucosal peptide hydrolases for glycylglycine, glycyl-L-leucine and L-leucylglycine, were assayed in 37 patients. Eight patients, four of whom had Crohn's disease, were found to have a marked reduction in the activity of glycylglycine dipeptidase and, to a lesser extent, of the other two hydrolases. Although absorption of glycine in the two groups was similar, there was...

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Dipeptidase deficiency and malabsorption of glycyiglycine in disease states '

The activities of jejunal mucosal peptide hydrolases for glycylglycine, glycyl-L-leucine and L-leucylglycine, were assayed in 37 patients. Eight patients, four of whom had Crohn's disease, were found to have a marked reduction in the activity of glycylglycine dipeptidase and, to a lesser extent, of the other two hydrolases. Although absorption of glycine in the two groups was similar, there was...

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ژورنال

عنوان ژورنال: Gut

سال: 1971

ISSN: 0017-5749

DOI: 10.1136/gut.12.4.276